Scientists have unveiled a revolutionary protospacer adjacent motif (PAM)-less genome editing system using CRISPR-SpRY, marking a major advancement in soybean ...
This study is led by Professor Jun Li (College of Life Sciences, Hebei Agricultural University, Baoding, Hebei, China). The authors used Cas9 variants to expand the targeting of CRISPR/ Cas9-mediated ...
But there's a hitch: CRISPR needs a password, a specific DNA signal called a PAM (protospacer adjacent motif), located next to the target gene, before it can make a cut. No password, no edit "It's ...
The team published its results in the journal Nature Communications ("TracrRNA reprogramming enables direct PAM-independent detection of RNA with diverse DNA-targeting Cas12 nucleases"). Bacteria have ...
At the end of 2023, the FDA approved Casgevy for sickle cell disease, its first approval for a therapeutic that used the genome editing tool clustered regulatory interspaced palindromic repeats ...
In the world of biopharmaceutical innovation, 2024 will be remembered as CRISPR’s breakout year. In the spring, five patients with sickle cell disease began treatment with Casgevy, the first ...
CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results