DNA hybridization thermodynamics is critical for accurate design of oligonucleotides for biotechnology and nanotechnology applications, but parameters currently in use are inaccurately extrapolated ...

Nucleic acids may be labeled at their 3’ end, 5’ end, or throughout the molecule, depending on the desired application. Myriad of enzymatic or chemical methods are utilized to generate nucleic acids ...

A DNA strand (purple) primes exponential amplification of DNA (red) as signals for directing light emission of DNA nanodeveices. [Organic and Biomolecular Chemistry] Scientists in Japan say they have ...

A few years back, the 50th anniversary of the discovery of the structure of the DNA double helix by biologists James D. Watson and Francis H. C. Crick was grandly celebrated. In fact, it's a double ...

Nucleic acids such as DNA and RNA play a central role in gene therapies and vaccines. They store and transmit biological ...