The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to map the 3D organization of the human genome and how it changes over time, ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

DNA might be too small to see with the unaided eye, but it packs our cells in shocking quantities: More than six and a half feet of DNA lies within every cellular nucleus. It squeezes into such a ...

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...